Factors Affecting Muscle Glycogen Synthetase Activity
نویسندگان
چکیده
منابع مشابه
Factors affecting muscle glycogen synthetase activity. IV. Comparative study of the different dependent forms of glycogen synthetase.
The properties of the glucose 6-phosphate-dependent forms of glycogen synthetase obtained by incubation with calcium ions or with adenosine triphosphate were compared. The two preparations showed different sensitivity to the action of heat and trypsin. In addition, the synthetase obtained with adenosine triphosphate is reconvertible to the independent form while that prepared with Ca++ is not. ...
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Glycogen synthetase (uridine diphosphate glucose-glycogen glucosyltransferase, EC 2.4.1.11) has been extensively studied in liver and in skeletal muscle (3-8). In extracts from a variety of tissues, measurements of the activity of the enzymes catalyzing the steps from n-glucose 6-phosphate to glycogen suggested that glycogen synthetase was rate-limiting and, hence, was likely to be important in...
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1. Isopenicillin N synthetase (IPNS) from Cephalosporium acremonium, which requires Fe2+ and O2 for activity, was highly purified for studies of factors affecting its conversion of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine (LLD-ACV) into isopenicillin N (IPN). EDTA was used to quench the reaction by removal of Fe2+. 2. IPNS was inactivated during the course of the conversion of LLD-ACV ...
متن کاملFactors affecting the activity of muscle phosphorylase b kinase.
Resting muscle contains a higher proportion of phosphorylase b than of phosphorylase a as determined by analysis of extracts (1). Under the influence of epinephrine (2, 3) or with muscle contraction (4), the amount of phosphorylase a increases. Two enzymes which arc involved in the interconversion of the two forms of phosphorylase have been described. One of these, phosphorylase 6 kinasc, catal...
متن کاملHepatic glycogen synthetase deficiency
In the 13 years since hepatic glycogen synthetase deficiency was first described in identical twins no further cases seem to have been observed. We report a child who had suffered from occasional morning convulsions since the age of 7. Three 24-hour metabolic profiles showed fasting hypoglycaemia, hyperketonaemia, but normal lactate. Hyperglycaemia and hyperlactataemia occurred after meals. Glu...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1967
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)96168-5